David’s attempt to help his patient, Mr. Brian Ogilvie, overcome his fear of squirrels takes a deadly turn, and exacerbates David’s depression. It has been five years since his favourite patient Michael moved to Toronto, and David is on a downward spiral. Their once twice-weekly sessions are now FaceTime chats every two months. Struggling to find happiness with his impending divorce from Sammy, the death of Mr. Ogilvie and the void left by Michael, David takes the advice of his personal therapist, Dr. Wasserman and starts a “depression journal.” Sammy insists David attend an awards show when their TV show is nominated. A few too many bottles of wine at the awards ceremony followed by an ill-advised dose of therapeutic marijuana sets David on an emotional rollercoaster that ends in conflagration; both emotionally and literally. Michael is adjusting to life in Toronto – building a successful career and living a relatively stress-free life. Michael gets a promotion after a successful presentation at work, but is quickly resistant when his boss tells him he has to leave by plane for Calgary that night. When plans change at the airport, Michael suffers an anxiety attack and boards a bus to Ottawa.